Catalent Spray Dried Dispersions Lipid-based Drug Delivery Catalent can partner with you to accelerate and optimize your molecule through the clinic and all the way to market ensuring robust and scalable formulations and integrated clinical manufacturing to accelerate your program with full clinical packaging and distribution services as well Dec 01 2013A commercial spray-dried inulin (Raftiline ST – 90% inulin DP ≥ 10) obtained from chicory roots was supplied by Beneo-Orafti (Tienen Belgium) Oregano (Origanum vulgare L ) was produced in Alentejo region in the south of Portugal The essential oil was obtained by steam distillation of dry flowers and leaves and stored in the dark at

Characterization of the Physical State of Spray

CiteSeerX - Document Details (Isaac Councill Lee Giles Pradeep Teregowda): Abstract Modulated differential scanning calorimetry wide angle x-ray scattering and environmental scanning electron microscopy were used to investigate the physical and mor-phological properties of chicory root inulin spray dried under different conditions When the feed

May 23 2007In contrast to the production and handling of powders for oral dosage forms methods to prepare stable biopharmaceutical powders are limited due to the sensitivity of peptides and proteins to powder processing conditions 4 6 Furthermore bulk properties such as size distribution or density of the final particles are different depending on the application 4 5 7

A basic understanding of the principles underlying molecular properties in the amorphous state is essential for those involved in stability studies any type of bulk drug manufacturing suspension characterization or solid dosage design evaluation and

The disclosure relates to live biotherapeutic products probiotics pharmaceutical compositions comprising said probiotics and methods of using them to treat various human diseases In some aspects the disclosure provides such compositions comprising strains of the bacterium Streptococcus australis and their uses in treating metabolic-related diseases or disorder

gum-inulin and at 0 8 and 20% concentration of gum-cream respectively Minimum fat in cream samples was produced at 0 2 and 1 2% concentration of gum-inulin and at 0 2 and 18% concentration of gum-cream respectively The linear expression of gum was significant showing the effectiveness of mastic gum on fat content of low fat cream

Characterization of the Physical State of Spray

Jul 20 2007Abstract Modulated differential scanning calorimetry wide angle x-ray scattering and environmental scanning electron microscopy were used to investigate the physical and morphological properties of chicory root inulin spray dried under different conditions When the feed temperature increased up to 80 C the average degree of polymerization of the

SEM micrographs spray dried samples with 1 0 and 2 0 wt% of PAA are presented in Figures 06 and 07 Samples obtained from slurries with 2 0wt% PAA have more porosity than that with 1 0wt%PAA in agreement with density values Although densities are very similar microstructures showed some differences

The disclosure relates to live biotherapeutic products probiotics pharmaceutical compositions comprising said probiotics and methods of using them to treat various human diseases In some aspects the disclosure provides such compositions comprising strains of the bacterium Gemella sanguinis and their uses in treating metabolic-related diseases or disorder

'Solid-state characterization of spray-dried ice cream mixes' Vega C Kim EHJ Chen XD Roos YH (2005) 'Solid-state characterization of spray-dried ice cream mixes' 'The physical state of amorphous corn starch and its impact on crystallization' (2010) Influence of inulin and storage temperature on stability of oil in water emulsions

EMA 5646 Ceramic Processing Zhe Cheng (2015) 3 Powder Characterization Characteristics Properties of Ceramics Characteristics of a material "parameters that specify the chemical and physical aspects of its composition and structure" (Reed (1995) p 69) Composition Structure Properties of a material

Treatment-2 containing physical mixture showed delayed t max (2 hours) on the three days of treatment in contrast to 1 hour t max obtained from paracetamol alone (treatment-1) and the two spray-dried formulations (treatments 2 and 3) This behavior can be attributed to faster absorption and longer stability of paracetamol released from SPD5

spray-dried powder The physical properties estimated were the glass transition temperature (Tg) and the crystallinity index investigated by modulated differential scanning calorimetry (MDSC) andwide angle x-ray scattering (WAXS) respectively lnaddition environmental scanning electron microscopy (ESEM) wasused forthesurface andpartiele shapecharacterization

Jan 07 2019Lyophilized and spray-dried biopharmaceutical formulations are used to provide long-term stability for storage and transport but questions remain about the mol In Situ Characterization of the Microstructural Evolution of Biopharmaceutical Solid-State Formulations with Implications for Protein Stability | NIST

Preparation and structural characterization of amorphous

In this work the solubility of tenoxicam is enhanced using amorphous spray-dried dispersions (SDDs) prepared using two molar equivalents of l-arginine and optionally with 10%-50% (w/w) polyvinylpyrrolidone (PVP) When added to the dispersions PVP is shown to improve physical properties and also assists in maintaining supersaturation in solution

Inulin is a water soluble storage polysaccharide and belongs to a group of non-digestible carbohydrates called fructans Inulin has attained the GRAS status in USA and is extensively available in about 36 000 species of plants amongst chicory roots are considered as the richest source of inulin C

PHYSICAL STABILITY OF SPRAY DRIED SOLID DISPERSIONS OF AMORPHOUS TOLFENAMIC ACID AND POLYVINYLPYRROLIDONE K-30 manipulation of solid state properties The intension is to produce small amorphous particles prepared characterization Dissolution XRPD TGA SEM Stability study Spray drying Drug content FTIR

Anina Seidemo 1 Patrick M Lehmann 1 Anna Rydhg 2 Ronnie Wirestam 1 Xiang Xu 3 4 Akansha A Sehgal 3 4 Yi Zhang 5 Frederik Testud 6 Pia C Sundgren 7 8 Peter C M van Zijl 3 4 and Linda Knutsson 1 3 1 Department of Medical Radiation Physics Lund University Lund Sweden 2 Centre for Medical Imaging and Physiology Skne University Hospital Lund and

Characterization of the spray dried protein regarding the particle morphology the physical state the residual content of water and other organic solvent the glass transition temperature and the biological activity should be used as criteria

DOI: 10 17533/udea vitae v22n2a02 PHARMACEUTICAL INDUSTRY PHYSICAL CHARACTERIZATION OF FREEZE-DRIED FOAM PREPARED FROM Aloe vera GEL AND GUAR GUM CARACTERIZACIN DE ESPUMAS LIOFILIZADAS PREPARADAS A PARTIR DE GEL DE Aloe vera Y GOMA GUAR Vernica SANTACRUZ-VZQUEZ PhD 1* Claudia

BibTeX MISC{Ronkart07characterizationof author = {Sbastien N Ronkart and Claude Deroanne and Michel Paquot and Christian Fougnies and Jean-christophe Lambrechts and Christophe S Blecker} title = {Characterization of the Physical State of Spray-Dried Inulin

Characterization of Spray-Dried Lansoprazole Enteric Microparticles Sci Pharm 2016 Apr-Jun 84(2):393-408 Epub 2015 Jul 29 Pharmacy Department Faculty of Technology and Engineering The M S University of Baroda Kalabhavan Vadodara-390001 Gujarat State India

A disconnect often exists between the solid state characterization data obtained and its implementation in the development of a process to isolate the target form of the API This gap needs to be bridged sooner so that as many early API batches produced as possible leverage the solid state characterization data in order to isolate a useful

The disclosure relates to live biotherapeutic products probiotics pharmaceutical compositions comprising said probiotics and methods of using them to treat various human diseases In some aspects the disclosure provides such compositions comprising strains of the bacterium Gemella sanguinis and their uses in treating metabolic-related diseases or disorder