Objective: To investigate the biological effects of the Mucuna pruriens (M pruriens) seed extracts that lacked l-DOPA which was formerly reported as the active ingredient on erectile dysfunction (ED) both in vitro and in vivo Methods: Seed of M pruriens plant that cultivated in Mae Taeng District Chiang Mai Province Thailand was collected International Journal of Biological Macromolecules is an established international journal of research into chemical and biological aspects of all natural macromolecules It presents the latest findings of studies on the molecular structure and properties of proteins macromolecular carbohydrates glycoproteins proteoglycans lignins biological poly-acids and nucleic acids

Biologically active compounds and pharmacological

Jun 01 2019Crocus spp accumulate apigenin acacetin luteolin and tricin derivatives but none of these compounds is widely presented inside Crocus genus The most abundant (identified in 23 of 49 species) are C-glycosylflavones of apigenin and luteolin derivatives

Biological weapons include any microorganism (such as bacteria viruses or fungi) or toxin (poisonous compounds produced by microorganisms) found in nature that can be used to kill or injure people The act of bioterrorism can range from a simple hoax to the actual use of these biological weapons also referred to as agents

1 1 Biologically Active Compounds Biologically active compounds often called bioactive compounds are by consensus defined as: "essential and nonessential compounds (e g vitamins or polyphenols) that occur in nature are part of the food chain and can be shown to have an effect on human health" (Biesalski et al 2009)

A phytochemical investigation of Saffron has been an isolated variety of biologically active constituents including crocin picrocrocin and safranal which is responsible for its distinct color aroma and medicinal properties Safranal is the major principle of active compounds constituting around 70% of total essential oil

Nov 29 20191 Nat Prod Res 2019 Nov 29:1-5 doi: 10 1080/14786419 2019 1696329 [Epub ahead of print] Blood orange (Citrus sinensis) as a rich source of nutraceuticals: investigation of bioactive compounds in different parts of the fruit by HPLC-PDA/MS

Spectroscopic Characterization of Crocetin Derivatives

Crocetin Esters Picrocrocin and Its Related Compounds Present in Crocus sativus Stigmas and Gardenia jasminoides Fruits Tentative Identification of Seven New Compounds by LC-ESI-MS Journal of Agricultural and Food Chemistry 2006 54 (3) 973-979

GUIDELINE ON THE INVESTIGATION OF BIOEQUIVALENCE DISCUSSION IN THE JOINT EFFICACY AND QUALITY WORKING GROUP December 1997 – reference medicinal products can be found in guidelines on similar biological medicinal products 5/27 for which active constituents are less well defined than for chemical entities

As part of an investigation of the biological activities of South African plants and due to their extensive traditional use and lack of scientific evidence a phytochemical and pharmacological investigation was performed on 17 indigenous Agathosma species (19 samples) The chemical composition of the essential oils was determined using

An unstable [t1/2 at 37 degrees = 32 +/- 2 (SD) sec] intermediate thromboxane A2 was detected in the conversion of prostaglandin G2 into 8-(1-hydroxy-3-oxopropyl)-9 12L-dihydroxy-5 10-heptadecadienoic acid (thromboxane B2) in platelets The intermediate was trapped by addition of methanol ethanol or sodium azide to suspensions of washed human platelets incubated for

The efficacy of Crocus sativus (Saffron) versus placebo and Fluoxetine in treating depression: a systematic review and meta-analysis Mojtaba Khaksarian 1 2 Masoud Behzadifar 1 Meysam Behzadifar 3 4 Maryam Alipour 5 Firouzeh Jahanpanah 3 Tania Simona Re 6–8 Fabio Firenzuoli 6 Riccardo Zerbetto 7 Nicola Luigi Bragazzi7–101Razi Herbal Medicines Research

Predicts many kinds of biological activity for compounds from different chemical series based on their 2D structural formulas PASS finds new targets mechanisms for some ligands It can reveal new ligands for some biological targets The tool can be used to analyze the occurrence in a database of compounds predicted to be active for a well-defined set of PASS activities

From ancient times the saffron Crocus sativus L has been widely used as a drug to promote health and fight disease especially in the Middle East and southeast Asia Saffron is cultivated in different parts of the world but currently mainly in Iran In view of its wide range of medical uses the saffron has undergone extensive phytochemical and biochemical studies and variety of

Mar 11 2014Saffron (Crocus sativus L stigma) the most valuable medicinal food product belongs to the Iridaceae family which has been widely used as a coloring and flavoring agent These properties are basically related to its crocins picrocrocin and safranal contents which have all demonstrated health promoting properties The present review article highlights the

Biological Warfare Facts History of Biological Agents

Biological weapons include any microorganism (such as bacteria viruses or fungi) or toxin (poisonous compounds produced by microorganisms) found in nature that can be used to kill or injure people The act of bioterrorism can range from a simple hoax to the actual use of these biological weapons also referred to as agents

Garlic (Allium sativum L ) is a widely consumed spice in the world Garlic contains diverse bioactive compounds such as allicin alliin diallyl sulfide diallyl disulfide diallyl trisulfide ajoene and S-allyl-cysteine Substantial studies have shown that garlic and its bioactive constituents exhibit antioxidant anti-inflammatory antibacterial antifungal immunomodulatory

739_55 ultrasonic extraction of active compounds from saffron 739_56 ALTERATIONS IN LIGNIN PEROXIDASE AND ASCORBATE PEROXIDASE ACTIVITIES IN CROCUS SATIVUS L CORMS EXPOSED TO COPPER 739_57 POLYPHENOL OXIDASE ACTIVITY DURING DEVELOPMENT OF SAFFRON (CROCUS SATIVUS L ) CORM

The solubility of metal ions such as Fe 3 + which form highly insoluble hydroxides depends on the pH and the presence of complexing agents In an oxygen-containing atmosphere iron exists as Fe(III) because of the positive reduction potential of Fe 3 + (Fe 3 + + e − → Fe 2 + E = +0 77 V) Because ferric hydroxide [Fe(OH) 3] is highly insoluble (K sp ≈ 1 10 −39) the equilibrium

Humulone as the active compound of hop extract was found to inhibit ear edema (inflammation) induced by 12‐O‐tetradecanoylphorbol‐13‐acetate Humulone (50% inhibition dose ID 50 0 2 mg/ear) had the same effect as indomethacin (ID 50 0 3 mg/ear) but a weaker effect than hydrocortisone (ID 50 0 03 mg/ear Yasukawa and others 1993 )

GUIDELINE ON THE INVESTIGATION OF BIOEQUIVALENCE DISCUSSION IN THE JOINT EFFICACY AND QUALITY WORKING GROUP December 1997 – reference medicinal products can be found in guidelines on similar biological medicinal products 5/27 for which active constituents are less well defined than for chemical entities

Saffron flower (Crocus sativus L ) has been obtained from the herbselers in the local markets in the city of Baghdad during March 2016 Saffron flower was prepared for extraction process in market research and consumer protection laboratories – Baghdad University Examining the Groups and active compounds existing

molecules Article Investigation of Organic Acids in Sa ron Stigmas (Crocus sativus L ) Extract by Derivatization Method and Determination by GC/MS Laurynas Jarukas 1 Olga Mykhailenko 2 Juste Baranauskaite 3 Mindaugas Marksa 1 * and Liudas Ivanauskas 1 1 Department of Analytical and Toxicological Chemistry Lithuanian University of Health Sciences A